Cyanoacetamide → HCID 20273630, compound

HRID 371318Notes

Reaction equation

HRID 371318 reaction equation
CN(C)[CH:3]=[C:4]([C:8]1[CH:13]=[CH:12][C:11]([CH2:14][C:15]([O:17]C)=[O:16])=[CH:10][CH:9]=1)[C:5](=O)[CH3:6].[C:20]([CH2:22][C:23]([NH2:25])=[O:24])#[N:21]>CN(C)C=O.C(O)C>[C:20]([C:22]1[C:23](=[O:24])[NH:25][C:5]([CH3:6])=[C:4]([C:8]2[CH:13]=[CH:12][C:11]([CH2:14][C:15]([OH:17])=[O:16])=[CH:10][CH:9]=2)[CH:3]=1)#[N:21]

Participants

4

Reactant 2

HCID 7898CyanoacetamideHCID 54335728HCID 54335728, compound

Product 1

HCID 20273630HCID 20273630, compound

Reagents, catalysts & solvents 1

HCID 19794673N,N-dimethylformamide ethanolSolvent

Procedure

11 g 4-dimethylamino-3-(4-methoxycarbonylmethylphenyl)-3-buten-2-one are reacted with cyanacetamide as described in Example 1. The title compound is obtained (m.p. 280°-282°--from dimethylformamide/ethanol).

Sources & evidence

ORD record
ord-d06945b80429440d9f6ddf2c2623ae2f
Source dataset
uspto-grants-1985_07
Patent number
US04530842

Reaction notes

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