反应详情

温度

0 °C

To a solution of 2-methyl-1-heptene 4 (17 g, 0.15 mol) in methylene chloride (300 mL) at 0° C. was added meta-chloroperbenzoic acid (37 g, 0.18 mol) in portions. The reaction mixture was stirred at 0° C. for 30 minutes, then at room temperature overnight. It was cooled in an ice bath and then filtered. The filtrate was washed with 5% sodium hydroxide, saturated sodium chloride and dried over magnesium sulfate; 7.8 g of 2-methyl-1-heptene oxide 5 was obtained after HPLC purification.

1. customat room temperature
2. customovernight
3. temperatureIt was cooled in an ice bath
4. filtrationfiltered
5. washThe filtrate was washed with 5% sodium hydroxide, saturated sodium chloride
6. dry with materialdried over magnesium sulfate