HCID 53882321, compound → 3-Chloro-1,4-dihydro-2,6-dimethyl-5-nitro-4-(3-nitrophenyl)pyridine

HRID 371421Notes

Reaction equation

HRID 371421 reaction equation
[NH2:1][C:2]([CH3:7])=[CH:3][N+:4]([O-:6])=[O:5].[Cl:8][C:9]([C:20](=O)[CH3:21])=[CH:10][C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([N+:17]([O-:19])=[O:18])[CH:12]=1>C(O)C>[Cl:8][C:9]1[CH:10]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([N+:17]([O-:19])=[O:18])[CH:12]=2)[C:3]([N+:4]([O-:6])=[O:5])=[C:2]([CH3:7])[NH:1][C:20]=1[CH3:21]

Participants

4

Reactant 2

HCID 53882321HCID 53882321, compoundHCID 714047121-Nitroprop-1-en-2-amine

Product 1

HCID 132420993-Chloro-1,4-dihydro-2,6-dimethyl-5-nitro-4-(3-nitrophenyl)pyridine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

0.1 mol of 2-amino-1-nitro-prop-1-ene and 0.1 mol of 2-chloro-1-(3-nitrophenyl)-but-1-ene-3-one were heated in boiling ethanol, analogously to Example 18. 3-Chloro-1,4-dihydro-2,6-dimethyl-5-nitro-4-(3-nitrophenyl)pyridine of melting point 198° C. (decomposition) was obtained. Yield:

Sources & evidence

ORD record
ord-1be33fe1ce1c4f71929282c25223a0bb
Source dataset
uspto-grants-1985_07
Patent number
US04532248

Reaction notes

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