Water → HCID 13478030, compound

HRID 371508Notes

Reaction equation

HRID 371508 reaction equation
Cl[CH2:2][C:3]([NH:5][C:6]1[CH:11]=[CH:10][C:9]([S:12]([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([Cl:21])[CH:16]=2)(=[O:14])=[O:13])=[CH:8][CH:7]=1)=[O:4].[N-:22]=[N+:23]=[N-:24].[Na+].O>C(O)C>[N:22]([CH2:2][C:3]([NH:5][C:6]1[CH:11]=[CH:10][C:9]([S:12]([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([Cl:21])[CH:16]=2)(=[O:14])=[O:13])=[CH:8][CH:7]=1)=[O:4])=[N+:23]=[N-:24]

Participants

5

Reactant 3

HCID 962WaterHCID 33557Sodium AzideHCID 13478029HCID 13478029, compound

Product 1

HCID 13478030HCID 13478030, compoundYield 58.9%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 2.0 g of 2-chloro-4'-(m-chlorophenylsulfonyl)acetanilide, 0.41 g of sodium azide, 20 ml of water and 40 ml of ethanol was refluxed for 3.5 hours and then evaporated to dryness. The residue was crystallized from ethanol, giving 1.2 g of 2-azido-4'-(m-chlorophenylsulfonyl)acetanilide, mp 125°-126° C.

Workup

  1. temperaturewas refluxed for 3.5 hours
  2. customevaporated to dryness
  3. customThe residue was crystallized from ethanol

Sources & evidence

ORD record
ord-befec4322a844fe492fbc07516dc2189
Source dataset
uspto-grants-1985_07
Patent number
US04532349

Reaction notes

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