Hydrogen Peroxide → 3-Butylsulphinyl-1,2,4-triazole

HRID 371572Notes

Reaction equation

HRID 371572 reaction equation
[CH2:1]([S:5][C:6]1[N:10]=[CH:9][NH:8][N:7]=1)[CH2:2][CH2:3][CH3:4].[OH:11]O>C(O)(=O)C>[CH2:1]([S:5]([C:6]1[N:10]=[CH:9][NH:8][N:7]=1)=[O:11])[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 178454955HCID 178454955, compound

Product 1

HCID 1784555543-Butylsulphinyl-1,2,4-triazole

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

To a solution of 15.7 g. 3-butylthio-1,2,4-triazole in 60 ml. glacial acetic acid was added 100 vol. hydrogen peroxide solution (11.4 ml., 1 molecular proportion). The reaction mixture was cooled occasionally during 1 hour to maintain the reaction temperature at 25° - 30° C., and then kept at room temperature for 24 hours. The resulting solution was distilled under reduced pressure to produce a solid residue which was recrystallized from ethyl acetate to give 3-n-butylsulphinyl-1,2,4-triazole, m.p. 82° - 83° C.

Workup

  1. temperatureThe reaction mixture was cooled occasionally during 1 hour
  2. temperatureto maintain the reaction temperature at 25° - 30° C.
  3. distillationThe resulting solution was distilled under reduced pressure
  4. customto produce a solid residue which
  5. customwas recrystallized from ethyl acetate

Sources & evidence

ORD record
ord-5009fbc1ed874e25a6910c80422db866
Source dataset
uspto-grants-1978_05
Patent number
US04087269

Reaction notes

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