反应详情

Adamantylamine (0.045 mole) and dimethyl (carboxymethyl)phosphonate (0.04 mole) were dissolved in 100 ml. of methylene chloride. As the solution was stirred, dicyclohexylcarbodiimide was added portionwise. The solution was stirred overnight, and the mixture filtered. The filtrate was concentrated to a solid. It was recrystallized from an appropriate solvent such as methanol. m.p. 190°-4° C.; yield, 32%.

1. stirringThe solution was stirred overnight
2. filtrationthe mixture filtered
3. concentrationThe filtrate was concentrated to a solid
4. customIt was recrystallized from an appropriate solvent such as methanol
5. customyield