HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Methyl 2-[1-(aminomethyl)cyclohexyl]acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | Gabapentin hydrochloride | HCID 6453919 | — |
| Product | Methyl 2-[1-(aminomethyl)cyclohexyl]acetate | HCID 21692047 | — |
Reaction Steps
In an analogous manner as described in Example 2, 1-aminomethyl-1-cyclohexane-acetic acid hydrochloride is reacted with methanol in the presence of hydrogen chloride. After evaporation in a vacuum the residue is recrystallised from methanol/ether to give pure methyl 1-aminomethyl-1-cyclohexane-acetate; m.p. 150° - 152° C. (hydrochloride)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04087544 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-6ddeb127eacb491e885913265c3b6ddb |
| Source note | uspto-grants-1978_05 |