HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 12795064, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 12794997 | HCID 12794997 | — |
| Reactant | HCID 12795004 | HCID 12795004 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 12795064 | HCID 12795064 | — |
Reaction Steps
By following the method of Example 2, methyl N-(2-hydroxyethyl)-3-carbomethoxy-4-methylpyrrole-2-acetate (IV, R = CH3) is converted into methyl N-(2-mesyloxyethyl)-3-carbomethoxy-4-methylpyrrole-2-acetate and then cyclized with sodium hydride in dimethylformamide, in accordance with the method of Example 8, to afford dimethyl 1,2-dihydro-6-methyl-3H-pyrrolo[1,2-a]pyrrole-1,7-dicarboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04087539 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-ecf5a3807c824f1f980b4d42d95bb793 |
| Source note | uspto-grants-1978_05 |