Calcium Carbonate → HCID 20356172, compound

HRID 371745Notes

Reaction equation

HRID 371745 reaction equation
[C:1]1([C:6]([C:8]2[N:12]3[CH2:13][CH2:14][CH:15]([C:16]([O-:18])=[O:17])[C:11]3=[CH:10][CH:9]=2)=[O:7])[S:5][CH:4]=[CH:3][CH:2]=1.[K+].C(=O)([O-])[O-].[Ca+2:24].[Cl-].[NH4+].[Ca]>Cl.O>[C:1]1([C:6]([C:8]2[N:12]3[CH2:13][CH2:14][CH:15]([C:16]([O-:18])=[O:17])[C:11]3=[CH:10][CH:9]=2)=[O:7])[S:5][CH:4]=[CH:3][CH:2]=1.[Ca+2:24].[C:1]1([C:6]([C:8]2[N:12]3[CH2:13][CH2:14][CH:15]([C:16]([O-:18])=[O:17])[C:11]3=[CH:10][CH:9]=2)=[O:7])[S:5][CH:4]=[CH:3][CH:2]=1

Participants

7

Reactant 4

HCID 10112Calcium Carbonate2×HCID 25517Ammonium ChlorideHCID 5460341CalciumHCID 23713908HCID 23713908, compound2×

Product 1

HCID 20356172HCID 20356172, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 962WaterSolvent

Procedure

To a solution of 237 mg. of 5-(2-thenoyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid in 8 ml. of methanol is added 1 molar equivalent of potassium hydroxide, in the form of a 0.1N solution to yield a solution containing potassium 5-(2-thenoyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylate. A solution of 50 mg. of calcium carbonate dissolved in the minimum amount of 1N hydrochloric acid necessary to effect solution of the calcium carbonate, is buffered with 100 mg. of solid ammonium chloride, followed by the further addition of 5 ml. of water. The thus obtained buffered calcium solution is then added to the solution of potassium 5-(2-thenoyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylate and the precipitate which forms is collected by filtration, washed with water and air dried, to yield calcium 5-(2-thenoyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylate.

Workup

  1. customThe thus obtained
  2. filtrationthe precipitate which forms is collected by filtration
  3. washwashed with water and air
  4. customdried

Sources & evidence

ORD record
ord-bda327235b0d425fb3011dee293242f0
Source dataset
uspto-grants-1978_05
Patent number
US04087539

Reaction notes

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