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HRID371857

反应详情

EQUATION

反应方程式

HRID 371857 的结构方程式

REACTANTS

反应物

1
结构：CC(=O)O.CC(=O)O.C[C@@H]1CC2=CC(=O)C[C@H](C)[C@]2(CO)[C@H]2CC[C@]3(C)[C@@H](O)CC[C@H]3[C@H]12
HCID86734742

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@H]1CC2=CC(=O)C[C@H](C)[C@]2(CO)[C@H]2CC[C@]3(C)[C@@H](O)CC[C@H]3[C@H]12
HCID70585453

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO.C[O-].[Na+]
溶剂HCID23694274

Sodium methanolate methanol

C2H7NaO2

PROCEDURE

实验过程

17β, 19-Dihydroxy-1α,7α-dimethyl-4-androsten-3-one diacetate is dissolved under nitrogen in a sodium methoxide methanol solution at 0° C. and stirred at room temperature for about 2 hours. The solution is poured onto water and the solid collected by filtration. Recrystallization of the solid from acetonitrile yields the desired 17β,19-dihydroxy-1α,7α-dimethyl-4-androsten-3-one.

WORKUP

后处理

  1. additionThe solution is poured onto water
  2. filtrationthe solid collected by filtration
  3. customRecrystallization of the solid from acetonitrile