Bromine → N-(2-Amino-3-bromo-5-methoxy-benzyl)-morpholine

HRID 371875Notes

Reaction equation

HRID 371875 reaction equation
[NH2:1][C:2]1[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[CH:11][C:3]=1[CH2:4][N:5]1[CH2:10][CH2:9][O:8][CH2:7][CH2:6]1.[Br:17]Br>C(Cl)Cl>[NH2:1][C:2]1[C:14]([Br:17])=[CH:13][C:12]([O:15][CH3:16])=[CH:11][C:3]=1[CH2:4][N:5]1[CH2:6][CH2:7][O:8][CH2:9][CH2:10]1

Participants

4

Reactant 2

HCID 24408BromineHCID 20318983N-(2-Amino-5-methoxy-benzyl)-morpholine

Product 1

HCID 20319084N-(2-Amino-3-bromo-5-methoxy-benzyl)-morpholine

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

N-(2-Amino-3-bromo-5-methoxy-benzyl)-morpholine was prepared from N-(2-amino-5-methoxy-benzyl)-morpholine and bromine analogous to Exanple 9. Proof of structure by IR-, UV- and NMR-spectra. IR-spectrum (methylenechloride): 3280 cm-1NH2 ; 3420 cm-1NH2 ; 2830 cm-1OCH3 ; 2810 cm-1N-alkyl; 1480 cm-1C= C; 1590 cm-1C=C.

Sources & evidence

ORD record
ord-2fd6073daeaa47f38fa5fa906d8a8a63
Source dataset
uspto-grants-1978_05
Patent number
USRE029628

Reaction notes

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