Bromine → 2-Amino-3-bromo-N-cyclohexyl-N-ethyl-5-methoxy-benzylamine

HRID 371877Notes

Reaction equation

HRID 371877 reaction equation
[NH2:1][C:2]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][C:3]=1[CH2:4][N:5]([CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1)[CH2:6][CH3:7].[Br:20]Br>C(Cl)Cl>[NH2:1][C:2]1[C:17]([Br:20])=[CH:16][C:15]([O:18][CH3:19])=[CH:14][C:3]=1[CH2:4][N:5]([CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1)[CH2:6][CH3:7]

Participants

4

Reactant 2

HCID 24408BromineHCID 203191982-Amino-N-cyclohexyl-N-ethyl-5-methoxy-benzylamine

Product 1

HCID 203192332-Amino-3-bromo-N-cyclohexyl-N-ethyl-5-methoxy-benzylamine

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2-Amino-3-bromo-N-cyclohexyl-N-ethyl-5-methoxy-benzylamine was prepared from 2-amino-N-cyclohexyl-N-ethyl-5-methoxy-benzylamine and bromine analogous to Example 9. Proof of structure by IR-, UV- and NMR-spectra. IR-spectrum (methylenechloride): 3240 cm-1NH2 ; 3410 cm-1NH2 ; 2860 cm-1 aliphatic hydrocarbon; 2940 cm-1 aliphatic hydrocarbon; 2830 cm-1OCH3 ; 2800 cm-1N-ethyl (shoulder); 1480 cm-1C=C; 1590 cm-1C=C.

Sources & evidence

ORD record
ord-2428526235f242e6b557e7e2c0e87d7b
Source dataset
uspto-grants-1978_05
Patent number
USRE029628

Reaction notes

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