Bromine → HCID 20319235, compound

HRID 371881Notes

Reaction equation

HRID 371881 reaction equation
[NH2:1][C:2]1[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[CH:11][C:3]=1[CH2:4][N:5]1[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1.[Br:17]Br>C(Cl)Cl>[NH2:1][C:2]1[C:14]([Br:17])=[CH:13][C:12]([O:15][CH3:16])=[CH:11][C:3]=1[CH2:4][N:5]1[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1

Participants

4

Reactant 2

HCID 24408BromineHCID 20319076HCID 20319076, compound

Product 1

HCID 20319235HCID 20319235, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

N-(2-Amino-3-bromo-5-methoxy-benzyl)-piperidine was prepared from N-(2-amino-5-methoxy-benzyl)-piperidine and bromine analogous to Example 9. Proof of structure by IR-, UV- and NMR-spectra. IR-spectrum (methylenechloride): 3240 cm-1NH2 ; 3400 cm-1NH2 ; 2830 cm-1OCH3 ; 2790 cm-1N-alkyl; 1480 cm-1C=C; 1590 cm-1C=C.

Sources & evidence

ORD record
ord-d8e1eb29c8364834be3c8bfe5353da75
Source dataset
uspto-grants-1978_05
Patent number
USRE029628

Reaction notes

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