HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitric Acid → 3-Acetyl-1-(p-nitrophenyl)-3-azabicyclo[3.1.0]hexane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | 3-Acetyl-1-phenyl-3-azabicyclo[3.1.0]hexane | HCID 12891371 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | 3-Acetyl-1-(p-nitrophenyl)-3-azabicyclo[3.1.0]hexane | HCID 20352253 | — |
Reaction Steps
To a suspension of 3-acetyl-1-phenyl-3-azabicyclo[3.1.0]hexane in concentrated sulfuric acid is added concentrated nitric acid during 15 minutes at 0°-10° C. The resulting mixture is stirred at room temperature for 15 minutes and then poured onto ice. The product, 3-acetyl-1-(p-nitrophenyl)-3-azabicyclo[3.1.0]hexane, is collected by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04088652 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-d1b9fad4d8e34d0085c93e1a21f63a0a |
| Source note | uspto-grants-1978_05 |