HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 6-(3-Chloro-4-methoxyphenyl)-4,5-dihydro-3(2H)-pyridazinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Benzenebutanoic acid, 3-chloro-4-methoxy-gamma-oxo- | HCID 10060312 | — |
| Product | 6-(3-Chloro-4-methoxyphenyl)-4,5-dihydro-3(2H)-pyridazinone | HCID 10823876 | 84% |
Reaction Steps
This compound was prepared in 84% yield by reaction of 3-(3-chloro-4-methoxybenzoyl)propionic acid with hydrazine hydrate in ethanolic solution at reflux temperature for 5 hours. It had mp 194°-195° C after crystallisation from ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04088762 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-a74367ec920b4cb09440d2bd0f62957d |
| Source note | uspto-grants-1978_05 |