HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-[(2-Methylimidazo(1,2-a)pyridin 3-yl)methyl]benzonitrile hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 4-[(2-Methylimidazo(1,2-a)pyridin3-yl)methyl]benzonitrile | HCID 19032465 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-[(2-Methylimidazo(1,2-a)pyridin 3-yl)methyl]benzonitrile hydrochloride | HCID 19032464 | — |
Reaction Steps
A mixture of 5 g of the product of Stage C, 80 ml of ethyl acetate and 3.5 ml of 6.6N hydrochloric acid in ethanol was ice-cooled, separated, washed with ethyl acetate and dried under reduced pressure at 80° C. to obtain 5 g of the expected product melting at 230° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05420138 |
| Source dataset | uspto-grants-1995_05 |
| ORD ID | ord-b3cf45a581c645b7b3b59ebc105efcb5 |
| Source note | uspto-grants-1995_05 |