Trifluoroacetic acid → 4-Heptylbenzaldehyde

HRID 372141Notes

Reaction equation

HRID 372141 reaction equation
[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].FC(F)(F)[C:16](O)=[O:17]>C1N2CN3CN(C2)CN1C3>[CH2:1]([C:8]1[CH:9]=[CH:10][C:11]([CH:16]=[O:17])=[CH:12][CH:13]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acid2×HCID 14115Heptylbenzene

Product 1

HCID 109216344-Heptylbenzaldehyde

Reagents, catalysts & solvents 1

HCID 4101HexamethylenetetramineSolvent

Procedure

88 g of n-heptylbenzene are taken up in 50 ml of trifluoroacetic acid and 70 g of hexamethylenetetramine. The whole is refluxed for 12 hours after which the excess of trifluoroacetic acid is distilled off by means of a water jet airpump. The mixture is then poured in ice water and neutralized with soda. After extraction with ether the resulting ether solution is evaporated and the resulting 4-heptylbenzaldehyde is used for the following process step.

Workup

  1. distillationis distilled off by means of a water jet airpump
  2. additionThe mixture is then poured in ice water and neutralized with soda
  3. extractionAfter extraction with ether the resulting ether solution
  4. customis evaporated

Sources & evidence

ORD record
ord-2b83de849c744c66a54539a535829ef8
Source dataset
uspto-grants-1978_05
Patent number
US04089588

Reaction notes

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