反应详情

113 g of N-phenyl-N'-benzyl-urea were dissolved in 1000 g of o-dichlorobenzene; the solution was made acid with 2-ethyl-hexanoic acid and reacted with 72 g of dimethyl maleate. After a reaction time of 6 hours at 175° C, the solvent was distilled off and the residue triturated with ether. The product separated by suction filtration can be obtained pure by recrystallisation from toluene. The white crystals obtained have a melting point of 130° C and their structure was demonstrated by the IR and NMR spectra and elementary analysis.

1. distillationAfter a reaction time of 6 hours at 175° C, the solvent was distilled off
2. customthe residue triturated with ether
3. customThe product separated by suction filtration
4. customcan be obtained pure by recrystallisation from toluene
5. customThe white crystals obtained