Acetic Anhydride → N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

HRID 372392Notes

Reaction equation

[CH:1]1([NH2:11])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1.[C:12](OC(=O)C)(=[O:14])[CH3:13]>>[CH:1]1([NH:11][C:12](=[O:14])[CH3:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 180661,2,3,4-Tetrahydro-1-naphthylamine

Product 1

HCID 11063199N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

Procedure

1,2,3,4-Tetrahydro-1-naphthylamine is stirred with acetic anhydride to afford N-(1,2,3,4-tetrahydro-1-naphthyl)-acetamide, which is oxidized to N-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)acetamide by the method of Example 1.

Sources & evidence

ORD record: ord-7cfaeca3a0ac4efa8bb5a1dd26653470
Source dataset: uspto-grants-1978_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04091018

Reaction notes

Loading…