Pyrrolidine → HCID 54165967, compound

HRID 372558Notes

Reaction equation

HRID 372558 reaction equation
[NH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[O:6]=[C:7]1[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=2[CH:11]=[CH:10][CH2:9][CH2:8]1>C(O)C>[O:6]=[C:7]1[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=2[CH2:11][CH2:10][CH:9]([N:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)[CH2:8]1

Participants

4

Reactant 2

HCID 31268PyrrolidineHCID 12588414HCID 12588414, compound

Product 1

HCID 54165967HCID 54165967, compoundYield 100.4%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A solution of 7.1 g of pyrrolidine in 30 ml of ethanol was added to a solution of 7.9 g of 5-oxo-6,7-dihydro [5H] benzocycloheptene in 30 ml of ethanol and the mixture was stirred at room temperature for 30 minutes and was evaporated to dryness to obtain 11.5 g of 5-oxo-7-(Pyrrolidin-1-yl)-6,7,8,9-tetrahydro [5H] benzocycloheptene.

Workup

  1. customwas evaporated to dryness

Sources & evidence

ORD record
ord-35d619a567284f53ba5e6a24d25812e8
Source dataset
uspto-grants-1978_05
Patent number
US04091115

Reaction notes

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