Methylamine → HCID 20510263, compound

HRID 372640Notes

Reaction equation

HRID 372640 reaction equation
Cl[C:2]1[C:7]([C:8]#[N:9])=[C:6]([Cl:10])[N:5]=[C:4]([NH:11][CH3:12])[N:3]=1.Cl[C:14]1N=C(Cl)C(C#N)=C(NC)[N:15]=1.CN>>[Cl:10][C:6]1[C:7]([C:8]#[N:9])=[C:2]([NH:15][CH3:14])[N:3]=[C:4]([NH:11][CH3:12])[N:5]=1

Participants

4

Reactant 3

HCID 6329MethylamineHCID 20510179HCID 20510179, compound2×HCID 20510268HCID 20510268, compound

Product 1

HCID 20510263HCID 20510263, compound

Procedure

The crude reaction product of Example IX, approximately 19% 4,6-dichloro-2-methylamino-5-pyrimidinecarbonitrile and 72% 2,4-dichloro-6-methylamino-5-pyrimidinecarbonitrile, was treated with aqueous 40% methylamine in the manner of Example V, to give 4-chloro-2,6-bis(methylamino)-5-pyrimidinecarbonitrile; mp, 281°-284° C.

Sources & evidence

ORD record
ord-1a57708d70ae487b843274d6cd4d0fcc
Source dataset
uspto-grants-1978_05
Patent number
US04092150

Reaction notes

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