反应详情

A mixture of 1.0 g. of 6-(p-chlorophenyl)-3-hydrazinopyridazine and 0.65 g. of diisopropylethylamine in 25 ml. of dioxane are placed in a flask and warmed slightly. To this is added 0.5 g. (0.45 ml.) of ethyl chloroformate and the reaction is stirred for one hour. The dioxane is removed on a rotating evaporator and ethanol is added to the residue resulting in a precipitate. This precipitate is recrystallized from ethanol giving a yellow solid, m.p. 176°-180° C.

1. additionA mixture of 1.0 g
2. temperaturewarmed slightly
3. additionTo this is added 0.5 g
4. customThe dioxane is removed on a rotating evaporator and ethanol
5. additionis added to the residue
6. customresulting in a precipitate
7. customThis precipitate is recrystallized from ethanol giving a yellow solid, m.p. 176°-180° C.