Phosphorus oxychloride → HCID 20398287, compound

HRID 372701Notes

Reaction equation

HRID 372701 reaction equation
[CH3:1][C:2]1[C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([N+:14]([O-:16])=[O:15])[CH:9]=2)=[N:6][NH:5][C:4](=O)[CH:3]=1.P(Cl)(Cl)([Cl:20])=O>>[CH3:1][C:2]1[CH:3]=[C:4]([Cl:20])[N:5]=[N:6][C:7]=1[C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([N+:14]([O-:16])=[O:15])[CH:9]=1

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 12449539HCID 12449539, compound

Product 1

HCID 20398287HCID 20398287, compound

Procedure

A 22.7 g. portion of 5-methyl-6-(m-nitrophenyl)-3(2H)-pyridazinone in 230 ml. of phosphorus oxychloride is heated on a steam bath for 3 hours. The reaction mixture is poured portionwise into crushed ice with stirring. The resulting solid is collected by filtration, washed with water and then dried yielding 5-methyl-6-(m-nitrophenyl)-3-chloropyridazine, m.p. 169°-171° C.

Workup

  1. additionThe reaction mixture is poured portionwise
  2. custominto crushed ice
  3. filtrationThe resulting solid is collected by filtration
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-e5285ddbc8594a8a834fc164115028aa
Source dataset
uspto-grants-1978_05
Patent number
US04092311

Reaction notes

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