Methylhydrazine → HCID 14273121, compound

HRID 372709Notes

Reaction equation

HRID 372709 reaction equation
[C:1]1([C:7]2[N:12]=[N:11][C:10](Cl)=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:14][NH:15][NH2:16]>C(O)CCC>[C:1]1([C:7]2[N:12]=[N:11][C:10]([N:15]([CH3:14])[NH2:16])=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 6061MethylhydrazineHCID 885153-Chloro-6-phenylpyridazine

Product 1

HCID 14273121HCID 14273121, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

A mixture of 10.0 g. of 6-phenyl-3-chloropyridazine 7.8 g. of methylhydrazine and 75 ml. of n-butanol is refluxed 6 hours. The mixture is cooled and filtered to give product and the filtrate is concentrated and filtered to give additional product. The two crops of product are recrystallized from ethanol to give crystals, m.p. 145°-147° C.

Workup

  1. additionA mixture of 10.0 g
  2. temperatureThe mixture is cooled
  3. filtrationfiltered
  4. customto give product
  5. concentrationthe filtrate is concentrated
  6. filtrationfiltered
  7. customto give additional product
  8. customThe two crops of product are recrystallized from ethanol
  9. customto give crystals, m.p. 145°-147° C.

Sources & evidence

ORD record
ord-69ff6bf7740a4699944668cce1b36406
Source dataset
uspto-grants-1978_05
Patent number
US04092311

Reaction notes

Loading…