反应详情

A mixture of 5.0 g. of 6-(p-cyanophenyl)-3-chloropyridazine, 8.71 g. of t-butylcarbazate and 100 ml. of butanol are heated at reflux for 3 hours. The solvent is removed on a rotating evaporator. Water is added, the resulting product is recovered by filtration, washed with water, recrystallized from methanol and dried yielding a product having a m.p. 169°-171° C.

1. additionA mixture of 5.0 g
2. temperatureat reflux for 3 hours
3. customThe solvent is removed on a rotating evaporator
4. additionWater is added
5. filtrationthe resulting product is recovered by filtration
6. washwashed with water
7. customrecrystallized from methanol
8. customdried
9. customyielding a product