反应详情

A 10.0 g. portion of 6-(p-chlorophenyl)-3-chloropyridazine and 6.1 g. of methyl hydrazine in 125 ml. of butanol is mixed and heated at reflux overnight. The reaction mixture is cooled, filtered, the precipitate is washed with butanol and water and dried. Recrystallization from ethanol gives 6-(p-chlorophenyl)-3-(1-methylhydrazino)pyridazine.

1. temperatureheated
2. temperatureat reflux overnight
3. temperatureThe reaction mixture is cooled
4. filtrationfiltered
5. washthe precipitate is washed with butanol and water
6. customdried
7. customRecrystallization from ethanol