Methylhydrazine → HCID 20326515, compound

HRID 372716Notes

Reaction equation

HRID 372716 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[N:12][C:11](Cl)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[CH3:15][NH:16][NH2:17]>C(O)CCC>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[N:12][C:11]([N:16]([CH3:15])[NH2:17])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 6061MethylhydrazineHCID 122575023-Chloro-6-(4-chlorophenyl)pyridazine

Product 1

HCID 20326515HCID 20326515, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

A 10.0 g. portion of 6-(p-chlorophenyl)-3-chloropyridazine and 6.1 g. of methyl hydrazine in 125 ml. of butanol is mixed and heated at reflux overnight. The reaction mixture is cooled, filtered, the precipitate is washed with butanol and water and dried. Recrystallization from ethanol gives 6-(p-chlorophenyl)-3-(1-methylhydrazino)pyridazine.

Workup

  1. temperatureheated
  2. temperatureat reflux overnight
  3. temperatureThe reaction mixture is cooled
  4. filtrationfiltered
  5. washthe precipitate is washed with butanol and water
  6. customdried
  7. customRecrystallization from ethanol

Sources & evidence

ORD record
ord-e6eeeb061844403eb548b7221439e666
Source dataset
uspto-grants-1978_05
Patent number
US04092311

Reaction notes

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