反应详情

A 2.0 g. portion of 6-(p-chlorophenyl)-3-(1-methylhydrazino)pyridazine and 1.30 g. of diisopropylethylamine in 50 ml. of dioxane is warmed slightly in a flask. A 1.0 g. portion of ethyl chloroformate is added and the reaction mixture is stirred for one hour. The dioxane is removed on a rotary evaporator, ethanol and water are added to the residue and a precipitate results. The solid is recrystallized from ethanol to give a pure white solid, m.p. 170°-172° C.

1. customThe dioxane is removed on a rotary evaporator, ethanol and water
2. additionare added to the residue
3. customa precipitate results
4. customThe solid is recrystallized from ethanol
5. customto give a pure white solid, m.p. 170°-172° C.