反应详情

A solution of 5-bromo-2-pyridone (17.3 g 0.1 mole) in N-methylpyrrolidinone (250 ml.) and potassium thiophenoxide (18.1 g, 0.12 mole) is heated at reflux for 12 hours under a nitrogen atmosphere. The reaction mixture is cooled and diluted with water. The product is collected by filtration, washed with water and dried to yeild 5-(phenylthio)-2-pyridone.

1. temperatureat reflux for 12 hours under a nitrogen atmosphere
2. temperatureThe reaction mixture is cooled
3. filtrationThe product is collected by filtration
4. washwashed with water
5. dry with materialdried to yeild 5-(phenylthio)-2-pyridone