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HRID372862

反应详情

EQUATION

反应方程式

HRID 372862 的结构方程式

REACTANTS

反应物

3
结构：CCCC(N)C(=O)O
HCID824

(+-)-Norvaline

C5H11NO2

结构：CC(C)C[C@H](N)C(=O)O
HCID6106

L-Leucine

C6H13NO2

结构：CC[C@H]1OC(=O)C[C@@H](OC(C)=O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](OC(=O)CC(C)C)[C@H](C)O3)[C@H](N(C)C)[C@H]2O)[C@@H](CC=O)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO[C@@H]1O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]1OC
HCID6441094

Tylvalosin

C53H87NO19

PRODUCTS

生成物

1
结构：CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@H](N(C)C)[C@H]2O)[C@@H](CC=O)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO[C@@H]1O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]1OC
HCID5280440

Tylosin

C46H77NO17

PROCEDURE

实验过程

The conversion reaction was carried out in a manner similar to Example 4 with the same strain, in which L-leucine was used in substitution for DL-norvaline in Example 4 as the isovaleryl donor. About 400 mg of white crystals of 3-acetyl-4"-isovaleryltylosin were obtained from 3 g of tylosin.

WORKUP

后处理

  1. customThe conversion reaction