HuagongsheHuagongshe Chemistry Print Report · For research reference only
DL-norvaline → Tylosin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | DL-norvaline | HCID 824 | — |
| Reactant | L-Leucine | HCID 6106 | — |
| Reactant | Tylvalosin | HCID 6441094 | — |
| Product | Tylosin | HCID 5280440 | — |
Reaction Steps
The conversion reaction was carried out in a manner similar to Example 4 with the same strain, in which L-leucine was used in substitution for DL-norvaline in Example 4 as the isovaleryl donor. About 400 mg of white crystals of 3-acetyl-4"-isovaleryltylosin were obtained from 3 g of tylosin.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04092473 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-b9dba08818614ad680075d005b94535b |
| Source note | uspto-grants-1978_05 |