Acetic Anhydride → HCID 136029150, compound

Participants

Reaction Steps

A stirred mixture of 7-amino-4-oxo-2-(2-propoxyphenyl)-3,4-dihydropyrimido[4,5-d]pyrimidine (0.59 g)and acetic anhydride (5 ml) was heated under reflux for 1.5 hours Excess acetic anhydride was removed under reduced pressure. The solid residue was washed with water and triturated with hot methanol to yield the title compound, 0.57 g, m.p. 273°-4° C.

Provenance & Evidence