N,N-Dimethylethylenediamine → HCID 135670759, compound

HRID 372993Notes

Reaction equation

HRID 372993 reaction equation
CS[C:3]1[N:8]=[C:7]2[N:9]=[C:10]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[O:20][CH2:21][CH2:22][CH3:23])[NH:11][C:12](=[O:13])[C:6]2=[CH:5][N:4]=1.[CH3:24][N:25]([CH3:29])[CH2:26][CH2:27][NH2:28]>C(O)C>[CH3:24][N:25]([CH3:29])[CH2:26][CH2:27][NH:28][C:3]1[N:8]=[C:7]2[N:9]=[C:10]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[O:20][CH2:21][CH2:22][CH3:23])[NH:11][C:12](=[O:13])[C:6]2=[CH:5][N:4]=1

Participants

4

Reactant 2

HCID 66053N,N-DimethylethylenediamineHCID 1355223017-Methylthio-4-oxo-2-(2-propoxyphenyl)-3,4-dihydropyrimido[4,5-d]pyrimidine

Product 1

HCID 135670759HCID 135670759, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a similar manner to Example 13, reaction of 7-methylthio-4-oxo-2-(2-propoxyphenyl)-3,4-dihydropyrimido[4,5-d]pyrimidine (0.49 g) and N,N-dimethylethylenediamine (1.24 g) in ethanol (20 ml) yielded the title compound, 0.46 g, m.p. 181°-2° C. (recrystallised for methanol).

Workup

  1. customyielded
  2. customthe title compound, 0.46 g, m.p. 181°-2° C. (recrystallised for methanol)

Sources & evidence

ORD record
ord-70a861c14e194c00a71ce7386f50fa5a
Source dataset
uspto-grants-1992_11
Patent number
US05162316

Reaction notes

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