反应详情

Following the procedure of Example 5, a mixture of 5-(4-chlorobutyl)-3-phenyl-2-oxazolidinone (3.0 g, 0.01186 mol), 1-phenylpiperazine hydrochloride (2.35 g, 0.01186 mol), potassium carbonate (6.54 g, 0.0473 mol), and potassium iodide (1.0 g) in 1-butanol gave a liquid (4.1 g, 91% yield) which crystallized upon standing. Recrystallization from isopropanol/isopropyl/-ether and drying under high vacuum gave 1.44 g, mp 83°-85° C.