Hydrochloric Acid → HCID 19811369, compound

HRID 373071Notes

Reaction equation

HRID 373071 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[NH:9][C:8](=[O:10])[N:7]([CH2:11][CH2:12][N:13]3[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]3)[C:6]=2[CH:19]=1.Cl>C(O)C>[ClH:1].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[NH:9][C:8](=[O:10])[N:7]([CH2:11][CH2:12][N:13]3[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18]3)[C:6]=2[CH:19]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19811326HCID 19811326, compound

Product 1

HCID 19811369HCID 19811369, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 6-chloro-1,3-dihydro-1-(2-piperidinoethyl)-2H-benzimidazol-2-one in ethanol (30 ml) was added concentrated hydrochloric acid (330 μl ) and the mixture was allowed to stand for 4 hours. The separating crystals were collected by suction and dried at 60° C. under reduced pressure to give 1.05 g of 6-chloro-1,3-dihydro-1-(2-piperidinoethyl)-2H-benzimidazol-2-one hydrochloride.

Workup

  1. customThe separating crystals were collected by suction
  2. customdried at 60° C. under reduced pressure

Sources & evidence

ORD record
ord-d06532a2f9934f6d87ae80eb7fd20d5b
Source dataset
uspto-grants-1992_11
Patent number
US05162318

Reaction notes

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