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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 373085Generated: October 27, 2026

Malic Acid → HCID 19811573, compound

https://huagongshe.com/reaction/373085

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMalic AcidHCID 525—
ReactantN-[3-[2-(1H-imidazol-1-yl)ethoxy]phenyl]-4-(2-thienyl)-2-pyrimidinamineHCID 9820417—
SolventEthanolHCID 702—
ProductHCID 19811573HCID 19811573—

Reaction Steps

To a solution of 1.0 g of N-[3-[2-(1H- imidazol-1-yl)ethoxy]phenyl]-4-(2-thienyl)-2-pyrimidinamine in 10 ml of hot ethyl alcohol is added 5 ml of ethyl alcohol containing 0.37 g of malic acid. Crystals begin to form and the reaction mixture is cooled. The solid is collected by filtration, washed with ethyl alcohol and dried to afford the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05162328
Source datasetuspto-grants-1992_11
ORD IDord-945f90ea6da745e0a4dd50ae865c0771
Source noteuspto-grants-1992_11