HuagongsheHuagongshe Chemistry Print Report · For research reference only
Malic Acid → HCID 19811573, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Malic Acid | HCID 525 | — |
| Reactant | N-[3-[2-(1H-imidazol-1-yl)ethoxy]phenyl]-4-(2-thienyl)-2-pyrimidinamine | HCID 9820417 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 19811573 | HCID 19811573 | — |
Reaction Steps
To a solution of 1.0 g of N-[3-[2-(1H- imidazol-1-yl)ethoxy]phenyl]-4-(2-thienyl)-2-pyrimidinamine in 10 ml of hot ethyl alcohol is added 5 ml of ethyl alcohol containing 0.37 g of malic acid. Crystals begin to form and the reaction mixture is cooled. The solid is collected by filtration, washed with ethyl alcohol and dried to afford the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05162328 |
| Source dataset | uspto-grants-1992_11 |
| ORD ID | ord-945f90ea6da745e0a4dd50ae865c0771 |
| Source note | uspto-grants-1992_11 |