HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenylpiperazine → 1-[Bis(2,2-dimethylpropoxy)methyl]-4-phenylpiperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenylpiperazine | HCID 7096 | — |
| Reactant | 1,1-Bis(2,2-dimethylpropoxy)-N,N-dimethylmethanamine | HCID 78623 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 1-[Bis(2,2-dimethylpropoxy)methyl]-4-phenylpiperazine | HCID 19812302 | — |
Reaction Steps
A solution of 4-phenylpiperazine (0.162 g, 0.001 mol) and dimethylformamide dineopentyl acetal (0.346 g, 0.0015 mol) in anhydrous chloroform (5 mL) was refluxed for 10 hours. The solvent and excess reagent were removed (100° C./1 mm) to give the product in quantitative yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05162523 |
| Source dataset | uspto-grants-1992_11 |
| ORD ID | ord-13225cc0a0264e19bac3a7fc77ca1668 |
| Source note | uspto-grants-1992_11 |