Dimethylamine → 14620-87-2

HRID 373464Notes

Reaction equation

HRID 373464 reaction equation
[CH2:1]([O:5][CH:6]([CH3:12])[C:7](N(C)C)=[O:8])[CH2:2][CH2:3][CH3:4].[CH2:13]([O:17][CH:18]([CH3:22])[C:19]([OH:21])=[O:20])[CH2:14][CH2:15][CH3:16].CNC.C([C@H:29]1[CH2:34][CH2:33][C@H:32](C2C=CC([Mg]Br)=CC=2)[CH2:31][CH2:30]1)CC>C1COCC1>[CH2:13]([O:17][CH:18]([CH3:22])[C:19]([OH:21])=[O:20])[CH2:14][CH2:15][CH3:16].[CH2:1]([O:5][CH:6]([C:7]([C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)=[O:8])[CH3:12])[CH2:2][CH2:3][CH3:4]

Participants

7

Reactant 4

HCID 674DimethylamineHCID 1366840714620-87-2HCID 19810118HCID 19810118, compoundHCID 178447893HCID 178447893, compound

Product 2

HCID 1366840714620-87-2HCID 43801212HCID 43801212, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

To (R) 2-butoxy-N,N-dimethylpropanamide prepared from (R) 2-butoxypropionic acid and dimethylamine, a solution of 4-(trans-4'-propylcyclohexyl)phenylmagnesium bromide in THF is dropped. They are reacted and purified in the same manner as in Example 3 (1) to obtain (R) 4-trans-4'-propylcyclohexyl)phenyl (1-butoxyethyl) ketone.

Workup

  1. customThey are reacted

Sources & evidence

ORD record
ord-eacba07bc6f440a39a09499d79d4e817
Source dataset
uspto-grants-1992_11
Patent number
US05164112

Reaction notes

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