HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 19810492, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Azetidine | HCID 10422 | — |
| Reactant | 2-Tetralone | HCID 68266 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 19810492 | HCID 19810492 | — |
Reaction Steps
A solution of azetidine (6.8 g, 0.12 mol), 3,4-dihydro-2(1 H)-naphthalenone (14.6 g, 0.10 mol), and p-toluenesulphonic acid (1.5 g) in dichloromethane (200 ml) was heated under reflux for 3 h in an apparatus fitted for the continuous removal of water, cooled to room temperature, washed with dilute aqueous sodium carbonate, dried (MgSO4), and evaporated in vacuo to give the product as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05164385 |
| Source dataset | uspto-grants-1992_11 |
| ORD ID | ord-56ee45376a3a4bb58b9e5d3949ab4e29 |
| Source note | uspto-grants-1992_11 |