HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium → HCID 86746334, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | 5-Acetyl-1-phenyl-3-(prop-2-yn-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | HCID 19810638 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86746334 | HCID 86746334 | — |
Reaction Steps
A solution of 0.23 g of sodium in 25 ml of methanol is added to a suspension of 2.84 g of 1-phenyl-3-propargyl-5-acetyl barbituric acid prepared as described in Example I, in ml of methanol. The reaction mixture is left to stand overnight while stirring, after which the methanol is evaporated. The residue is stirred with diethyl ether, sucked off and dried. The title compound (8) is obtained in a yield of 2.62 g; melting-point >260° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05164396 |
| Source dataset | uspto-grants-1992_11 |
| ORD ID | ord-27b005abe9ff4de7a05f0f2e08710203 |
| Source note | uspto-grants-1992_11 |