HuagongsheHuagongshe Chemistry Print Report · For research reference only
[2-Butyl-5-chloro-1-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol → 2-Butyl-1-[(2'-{N-triphenylmethyltetrazol-5-yl}biphen-4-yl)methyl]-5-chloro-1H-imidazole-4-carboxaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [2-Butyl-5-chloro-1-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol | HCID 22373554 | — |
| Reactant | 2-butyl-1-[(2'-t-butoxycarbonylbiphen-4-yl)methyl]-5-chloro-1H-imidazole-4-methanol | HCID 131717644 | — |
| Product | 2-Butyl-1-[(2'-{N-triphenylmethyltetrazol-5-yl}biphen-4-yl)methyl]-5-chloro-1H-imidazole-4-carboxaldehyde | HCID 131717645 | — |
Reaction Steps
This Step A compound can be prepared as described in Example 3, Step A, except that 2-butyl-1-[(2'-{N-triphenylmethyltetrazol-5-yl}biphen-4-yl)-methyl]-5-chloro-1H-imidazole-4-methanol (European Patent Applications 253,310 and 291,969) can be used as the starting material for the oxidation instead of 2-butyl-1-[(2'-t-butoxycarbonylbiphen-4-yl)methyl]-5-chloro-1H-imidazole-4-methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05164407 |
| Source dataset | uspto-grants-1992_11 |
| ORD ID | ord-6d69b1225ec240f5b8747c702e23216a |
| Source note | uspto-grants-1992_11 |