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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 373612Generated: October 31, 2026

[2-Butyl-5-chloro-1-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol → 2-Butyl-1-[(2'-{N-triphenylmethyltetrazol-5-yl}biphen-4-yl)methyl]-5-chloro-1H-imidazole-4-carboxaldehyde

https://huagongshe.com/reaction/373612

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[2-Butyl-5-chloro-1-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanolHCID 22373554—
Reactant2-butyl-1-[(2'-t-butoxycarbonylbiphen-4-yl)methyl]-5-chloro-1H-imidazole-4-methanolHCID 131717644—
Product2-Butyl-1-[(2'-{N-triphenylmethyltetrazol-5-yl}biphen-4-yl)methyl]-5-chloro-1H-imidazole-4-carboxaldehydeHCID 131717645—

Reaction Steps

This Step A compound can be prepared as described in Example 3, Step A, except that 2-butyl-1-[(2'-{N-triphenylmethyltetrazol-5-yl}biphen-4-yl)-methyl]-5-chloro-1H-imidazole-4-methanol (European Patent Applications 253,310 and 291,969) can be used as the starting material for the oxidation instead of 2-butyl-1-[(2'-t-butoxycarbonylbiphen-4-yl)methyl]-5-chloro-1H-imidazole-4-methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05164407
Source datasetuspto-grants-1992_11
ORD IDord-6d69b1225ec240f5b8747c702e23216a
Source noteuspto-grants-1992_11