m-Chloroperbenzoic acid → HCID 70074082, compound

HRID 373767Notes

Reaction equation

HRID 373767 reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:10]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[S:17][CH2:18][CH2:19][CH2:20][CH:21]([N:23]2[CH2:28][CH2:27][N:26]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=3[O:35][CH3:36])[CH2:25][CH2:24]2)[CH3:22])[C:9]([N+:37]([O-:39])=[O:38])=[C:8]([CH3:40])[NH:7][C:6]=1[NH2:41])=[O:4].ClC1C=CC=C(C(OO)=[O:50])C=1>>[CH3:1][O:2][C:3]([C:5]1[CH:10]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[S:17]([CH2:18][CH2:19][CH2:20][CH:21]([N:23]2[CH2:28][CH2:27][N:26]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=3[O:35][CH3:36])[CH2:25][CH2:24]2)[CH3:22])=[O:50])[C:9]([N+:37]([O-:39])=[O:38])=[C:8]([CH3:40])[NH:7][C:6]=1[NH2:41])=[O:4]

Participants

3

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 70075402HCID 70075402, compound

Product 1

HCID 70074082HCID 70074082, compound

Procedure

This compound was prepared from 2-amino-1,4-dihydro-4-(2-{4-[4-(2-methoxyphenyl)-1-piperazinyl]-pentylthio}phenyl)-6-methyl-5-nitro-3-pyridinecarboxylic acid methyl ester and m-chloroperbenzoic acid in the same manner as described for Example 2. 1H-NMR (CDCl3) ∂ 1.65(br s,4H); 2.02(m,2H); 2.42(s,3H); 2.49(m,2H); 2.71(s,4H); 2.98(m,2H); 3.12(s,4H); 3.61(s,3H); 3.86(s,3H); 5.76(s,1H); 6.68(s,2H); 6.84-7.01(m,4H); 7.27(m,4H); 7.81-7.86(m,1H). Mass spectrum: 598 (M+H).

Sources & evidence

ORD record
ord-ef013c49b052482591830d31e24aa527
Source dataset
uspto-grants-1992_11
Patent number
US05166148

Reaction notes

Loading…