化工社化工社 化学情報印刷レポート · 研究参考用
4-Chlorophenyl Isocyanate → 1-(2-Methylthiobenzoyl)-3-(4-chlorophenyl)urea
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Chlorophenyl Isocyanate | HCID 7693 | — |
| 反応物 | 2-Methyl-thiobenzamide | HCID 816810 | — |
| 溶媒 | O-Xylene | HCID 7237 | — |
| 生成物 | 1-(2-Methylthiobenzoyl)-3-(4-chlorophenyl)urea | HCID 19808586 | — |
反応手順
2-Methylthiobenzamide in an amount of 1.67 g is suspended in 25 ml of dry xylene. After addition of 1.54 g of 4-chlorophenylisocyanate, the reaction mixture is refluxed over night. After cooling to room temperature the desired product crystallizes in a yield of 2.8 g, m.p. 211° C. The same result is obtained when 2-methylthiobenzoyl isocyanate is reacted with 4-chloroaniline.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05166180 |
| 出典データセット | uspto-grants-1992_11 |
| ORD ID | ord-3e9f87db5c6c47a4be9c7f15f23b8c67 |
| 出典メモ | uspto-grants-1992_11 |