反应详情

2-Methylthiobenzamide in an amount of 1.67 g is suspended in 25 ml of dry xylene. After addition of 1.54 g of 4-chlorophenylisocyanate, the reaction mixture is refluxed over night. After cooling to room temperature the desired product crystallizes in a yield of 2.8 g, m.p. 211° C. The same result is obtained when 2-methylthiobenzoyl isocyanate is reacted with 4-chloroaniline.

1. temperaturethe reaction mixture is refluxed over night