Phenylhydrazine → HCID 86746349, compound

Participants

Reaction Conditions

Reaction Steps

Phenylhydrazine (4.0 ml) was added to 5.00 g 1-(4-amino-3-pyridinyl)ethanone, and the mixture was stirred at 100° C. for seventeen hours. A similar procedure was followed using 4.0 g 1-(4-amino-3-pyridinyl)ethanone and 3.20 ml phenylhydrazine. The products of the two reactions were combined and purified by flash chromatography to yield 9.74 g solid. Recrystallization of 1.24 g from CH3OH/water yielded 0.28 g solid, m.p. 168°-170° C.

Provenance & Evidence