Trifluoroacetic acid → HCID 19974025, compound

HRID 37389Notes

Reaction equation

HRID 37389 reaction equation
C(OC([NH:8][CH2:9][CH2:10][N:11]([C:15](=[O:20])[C:16]([F:19])([F:18])[F:17])[CH2:12][CH:13]=[CH2:14])=O)(C)(C)C.[F:21][C:22]([F:27])([F:26])[C:23]([OH:25])=[O:24]>C(Cl)Cl>[F:21][C:22]([F:27])([F:26])[C:23]([OH:25])=[O:24].[F:17][C:16]([F:18])([F:19])[C:15]([N:11]([CH2:12][CH:13]=[CH2:14])[CH2:10][CH2:9][NH2:8])=[O:20]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 15814420N-(t-butyloxycarbonyl)-N'-(trifluoroacetyl)-N'-(allyl)ethylenediamine

Product 1

HCID 19974025HCID 19974025, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Dissolve N-(t-butyloxycarbonyl)-N'-(trifluoroacetyl)-N'-(allyl)-ethylenediamine (1.95 mmol) in methylene chloride (7 mL) and add trifluoroacetic acid (2.6 mL). Stir at room temperature for 1 hour then evaporate the solvent in vacuo to give N'-(trifluoroacetyl)-N'-(allyl)-ethylenediamine trifluoroacetate

Workup

  1. customthen evaporate the solvent in vacuo

Sources & evidence

ORD record
ord-88adb4c50a2a4517a956bd279f0f86b2
Source dataset
uspto-grants-1995_05
Patent number
US05420271

Reaction notes

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