Hydrochloric Acid → HCID 19808795, compound

HRID 374034Notes

Reaction equation

HRID 374034 reaction equation
[ClH:1].C([NH:5][CH2:6][CH2:7][N:8]1[C:24](=[O:25])[C:23]2[C:22]3[C:21]4[C:16](=[CH:17][CH:18]=[C:19]([O:26][CH3:27])[CH:20]=4)[NH:15][C:14]=3[C:13]([CH3:28])=[CH:12][C:11]=2[C:9]1=[O:10])(=O)C>C(O)C>[ClH:1].[NH2:5][CH2:6][CH2:7][N:8]1[C:24](=[O:25])[C:23]2[C:22]3[C:21]4[C:16](=[CH:17][CH:18]=[C:19]([O:26][CH3:27])[CH:20]=4)[NH:15][C:14]=3[C:13]([CH3:28])=[CH:12][C:11]=2[C:9]1=[O:10]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19808726HCID 19808726, compound

Product 1

HCID 19808795HCID 19808795, compoundYield 68%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

20 ml of ethanol and 10 ml of concentrated hydrochloric acid were added to 150 mg of N-(2-acetylaminoethyl)- 6-methoxy-1-methylcarbazole-3,4-dicarboximide. The mixture was refluxed for 15 hours and then cooled to room temperature. The resulting crystals were collected by filtration, washed with ethanol, and dried to obtain 100 mg (yield: 68%) of N-(2-aminoethyl)-6-methoxy-1-methylcarbazole-3,4-dicarboximide hydrochloride as yellow crystals.

Workup

  1. temperatureThe mixture was refluxed for 15 hours
  2. filtrationThe resulting crystals were collected by filtration
  3. washwashed with ethanol
  4. customdried

Sources & evidence

ORD record
ord-5d7ab8c1cd794f9ab615adc80b35c467
Source dataset
uspto-grants-1992_11
Patent number
US05166204

Reaction notes

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