Hydrochloric Acid → HCID 19808778, compound

HRID 374041Notes

Reaction equation

HRID 374041 reaction equation
[CH3:1][N:2]([CH3:24])[CH2:3][CH2:4][N:5]1[C:13](=[O:14])[C:12]2[C:11]3[C:15]4[CH:21]=[CH:20][CH:19]=[CH:18][C:16]=4[O:17][C:10]=3[C:9]([CH3:22])=[CH:8][C:7]=2[C:6]1=[O:23].[ClH:25]>C(Cl)(Cl)Cl>[ClH:25].[CH3:24][N:2]([CH3:1])[CH2:3][CH2:4][N:5]1[C:13](=[O:14])[C:12]2[C:11]3[C:15]4[CH:21]=[CH:20][CH:19]=[CH:18][C:16]=4[O:17][C:10]=3[C:9]([CH3:22])=[CH:8][C:7]=2[C:6]1=[O:23]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19808700HCID 19808700, compound

Product 1

HCID 19808778HCID 19808778, compoundYield 84%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

In 10 ml of chloroform was dissolved 150 mg of 2-(2-dimethylaminoethyl)-5-methyl-1H-benzofuro[3,2-e]-isoindole-1,3(2H)-dione. Into the solution was introduced hydrogen chloride gas with ice cooling, until the solution was saturated with the gas. The resulting solution was stirred for 10 minutes with ice cooling. The resulting crystals were collected by filtration and dried to obtain 140 mg (yield: 84%) of 2-(2-dimethylaminoethyl)-5-methyl-1H-benzofuro[3,2-e]isoindole-1,3(2H)-dione hydrochloride as light yellow crystals.

Workup

  1. filtrationThe resulting crystals were collected by filtration
  2. customdried

Sources & evidence

ORD record
ord-dbd9cf35363b49fc9508da3f950934ae
Source dataset
uspto-grants-1992_11
Patent number
US05166204

Reaction notes

Loading…