HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 6-Acetylamino-1-benzyl-4-methylhexahydro-1H-1,4-diazepine | HCID 10355307 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | Acetate | HCID 175 | — |
| Product | 6-acetylamino-1-methylhexahydro-1H-1,4-diazepine | HCID 15206155 | — |
Reaction Steps
6-Acetylamino-1-benzyl-4-methylhexahydro-1H-1,4-diazepine (20 g) is dissolved in ethanol (400 ml) and acetic acid (70 ml), and hydrogenated over 10% palladium on carbon (2 g) at about 50° C. After the calculated amount of the hydrogen is absorbed, the catalyst is filtered off. The filtrate is evaporated under reduced pressure to give acetate of the title compound (30 g) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05166341 |
| Source dataset | uspto-grants-1992_11 |
| ORD ID | ord-7a57642378f242089de0f8efeb778db7 |
| Source note | uspto-grants-1992_11 |