Hydrochloric Acid → 6-(1-Hydroxy-1-Phenylmethyl)Benzothiazolinone

HRID 374119Notes

Reaction equation

HRID 374119 reaction equation
[C:1]([C:9]1[CH:18]=[CH:17][C:12]2[N:13]=[CH:14][S:15](=[O:16])[C:11]=2[CH:10]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[BH4-].[Na+].Cl>C(=O)([O-])[O-].[Na+].[Na+]>[OH:8][CH:1]([C:9]1[CH:18]=[CH:17][C:12]2[N:13]=[CH:14][S:15](=[O:16])[C:11]=2[CH:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 4311764Sodium borohydrideHCID 1317171596-Benzoylbenzothiazolinone

Product 1

HCID 1317176226-(1-Hydroxy-1-Phenylmethyl)Benzothiazolinone

Reagents, catalysts & solvents 1

HCID 10340Sodium CarbonateSolvent

Procedure

0.02 mol of 6-benzoylbenzothiazolinone obtained in Example 1 are dissolved in 80 cm3 of 30% aqueous sodium carbonate solution in a 250 cm3 flask 0.015 mol of sodium borohydride are added slowly, with agitation. The agitation is maintained for 16 hours at ambient temperature, followed by acidification with hydrochloric acid diluted 1:1. The precipitate formed is drained, washed with water and dried.

Workup

  1. additionare added slowly, with agitation
  2. additiondiluted 1:1
  3. customThe precipitate formed
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-6db93b28b978419ebe4a1ca0e710ca12
Source dataset
uspto-grants-1992_11
Patent number
US05166353

Reaction notes

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