Methanol → HCID 19809611, compound

HRID 374247Notes

Reaction equation

HRID 374247 reaction equation
[CH3:1][P:2]([O:6]C)(=O)OC.[C:8]([OH:13])(=[O:12])[C:9]([CH3:11])=[CH2:10].[CH3:14]O>>[CH3:14][P:2]([CH3:1])([CH2:10][CH:9]([CH3:11])[C:8]([OH:13])=[O:12])=[O:6]

Participants

4

Reactant 3

HCID 887MethanolHCID 4093Methacrylic AcidHCID 12958Dimethyl methylphosphonate

Product 1

HCID 19809611HCID 19809611, compoundYield 41.3%

Procedure

108 g of dimethyl methanephosphonate are added dropwise at 70° C. to a solution of 86 g of methacrylic acid and 32 g of methanol in the course of 30 minutes. After a reaction time of 3 hours the reaction mixture is worked up by vacuum distillation. 59 g of 3-(dimethylphosphinyl)-2-methylpropionic acid are obtained with a 91.1% purity, which corresponds to a theoretical yield of 29.5%.

Workup

  1. distillationAfter a reaction time of 3 hours the reaction mixture is worked up by vacuum distillation

Sources & evidence

ORD record
ord-0b4261a1092b4ab7a931ae8a6e987f1d
Source dataset
uspto-grants-1992_11
Patent number
US05166385

Reaction notes

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